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Incyte to Provide Update on Clinical Programs at Cowen Health Care ... - Mar 17, 2008
Business Wire (press release),Myelofibrosis is a serious neoplastic condition characterized by bone marrow failure, life-threatening splenic enlargement, and marked constitutional
Cytopia Nominates JAK2 Clinical Candidate for Myeloproliferative ... - Mar 17, 2008
Earthtimes,Myeloproliferative disorders are a group of diseases including myelofibrosis, polycythemia vera (PV) and essential thrombocythemia (ET) that affect over
Incyte hopes to fast-track first drug - Mar 8, 2008
The News Journal,The company's drug for treating myelofibrosis, a rare but fatal bone marrow disorder, showed promising results recently in an early-to-mid-stage clinical
Man died after operation - Feb 29, 2008
Evesham Journal,John Martin Denniss, 67, of Glebe Road, had a long history of illness, including 20 years of suffering from myelofibrosis along with osteoarthritis,
Flow Cytometry and Molecular Genetics for Hematologic Neoplasms - Mar 21, 2008
Medscape (subscription)The detection of JAK2 mutation by this technique is very important for the diagnosis of polycythemia vera, chronic idiopathic myelofibrosis, and essential
Casper coach learned, taught life's lessons through sports - Mar 18, 2008
Jackson Hole Star-Tribune,Ron was diagnosed with myelofibrosis, a serious bone marrow disease, in late 2006 and needed a bone marrow transplant. A son, Brian, from Ron's previous
New Genetic Test Detects Rare, Deadly, Difficult-to-Diagnose Blood ... - Mar 7, 2008
PR Web (press release),...(ET) and Idiopathic Myelofibrosis (IMF), and this new test may prove helpful for diagnosis and management of these disorders as more research is done.
Upbeat outlook on life - Feb 29, 2008
Journal Times,There are three basic disorders — polycythemia vera, essential thrombocytosis (also called essential thrombocythemia) and primary myelofibrosis.
Incyte Corporation Q4 2007 Earnings Call Transcript - Feb 18, 2008
Seeking Alpha,It not only offers the potential for a rapid development and approval path in myelofibrosis. It also affords multiple other opportunities for development in
Special Day Out Was A Real Tonic - Feb 18, 2008
Glasgow Daily Record,And now the former carer faces an uncertain future after being diagnosed with a rare form of cancer called myelofibrosis. She said: "I sometimes wonder what
Cytopia's JAK2 inhibitor shows potent activity - Jan 29, 2008
Trading Markets (press release),Progressive disease can lead MPD patients to develop leukemia or myelofibrosis. More than 95pc of patients with PV and about 50pc of patients with two
Incyte Reports Progress in Multiple Clinical Programs; Expands JAK ... - Feb 14, 2008
Business Wire (press release),...completing discussions with the FDA regarding a registration strategy for the myelofibrosis indication for INCB18424 in the first half and initiating
Exelixis Announces Full Year and Fourth Quarter 2007 Financial Results - Feb 14, 2008
Earthtimes,...initiate pivotal trials this year for XL647 for non-small cell lung cancer, XL184 for medullary thyroid cancer, and potentially XL019 for myelofibrosis.
TargeGen Announces Initiation of Clinical Trial of JAK2 Inhibitor ... - Feb 1, 2008
FOXBusiness...including polycythemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF). In preclinical models of myeloproliferative diseases,
Celgene Reports Record Fourth Quarter and Full Year 2007 Product ... - Jan 31, 2008
StreetInsider.com (subscription),Patients -- Submit Regulatory Filing for REVLIMID in Japan -- Advance CC-4047 Clinical and Regulatory Strategies in Myelofibrosis, Multiple Myeloma,
JAK2V617F mutation screening in WHO 2008 criteria - Jan 22, 2008
Laboratory Talk,...highlighted the revision in the 2008 WHO diagnostic criteria for Polycythemia Vera (PV), Essential Thrombocytemia (ET) and Primary Myelofibrosis (PMF).
Evidence Links Anemia Drugs With Leukemic Transformation In ... - Dec 10, 2007
Science Daily (press release)..."We believe this to be the first large systematic evaluation of the risk factors leading to leukemic transformation in primary myelofibrosis," says Dr.
Exelixis: positive results in Phase I data on Xl019, a ... - Dec 10, 2007
CNNMoney.com...by results from its ongoing Phase I trial of its investigational small molecule XL019 in patients with myelofibrosis, a myeloproliferative disorder.
EXEL: Presents Positive Ph I Update re XL019 in Myelofibrosis - Dec 10, 2007
Trading Markets (press release),Exelixis, Inc. (EXEL) reported phase 1 data today from an ongoing phase 1 trial of XL019 in patients with myelofibrosis, a myeloproliferative disorder (MPD)
Anemia drugs may raise blood cancer risk - study - Dec 11, 2007
ReutersMyelofibrosis is a bone marrow disorder that interrupts the body's normal production of blood cells, leading to severe anemia and enlargement of the spleen.
Exelixis Presents Encouraging Phase 1 Data For XL019, A Novel ... - Dec 10, 2007
CNNMoney.comWe are planning to initiate pivotal trials of XL019 in myelofibrosis patients in 2008." The phase 1 dose escalation study of XL019 is ongoing in subjects
Mayo Clinic Study Links Anemia Drugs to Leukemia Risk - Dec 10, 2007
New York Times,Mayo Clinic researchers reviewed records of 311 patients with primary myelofibrosis, a scarring of the bone marrow, from 1976 to 2006.
Data Presented At The American Society Of Hematology 49th Meeting ... - Dec 16, 2007
PR-USA.net (press release),Responses were evaluated using the IWG consensus criteria for treatment response in myelofibrosis. Enrollment in the study has been completed.
Incyte novel JAK Inhibitor INCB18424 shows positive results in ... - Dec 10, 2007
CNNMoney.comMyelofibrosis is a neoplastic condition with a survival rate of three to seven years, characterized by varying degrees of bone marrow failure,
Study Links ESAs To Higher Leukemia Risk For Some - Dec 11, 2007
BioWorld Online,In a retrospective study examining 30 years of records of 311 patients with myelofibrosis, a disorder in which the body's normal production of blood cells
Amgen stock falls on rekindled anemia drug woes - Dec 10, 2007
Reuters...or ESAs, may be associated with a higher risk leukemia among people with a rare bone marrow disorder called myelofibrosis.
Exelixis Reports Data From Ongoing Phase 1 Study Of XL019 To Treat ... - Dec 10, 2007
RTT News,We are planning to initiate pivotal trials of XL019 in myelofibrosis patients in 2008.� EXEL's shares are currently trading at $8.66, up 19 cents or 2.15%
Epogen Side Effects: Anemia and Heart Attack - Dec 28, 2007
Lawyers and Settlements...drugs might be involved in the development of a form of leukemia when they are used to treat people with a rare blood disorder known as myelofibrosis.
Pivotal Phase 3 NPLATE(TM) Study in Non-Splenectomized Patients ... - Dec 10, 2007
WELT ONLINE,...of which three patients were withdrawn from the study due to vaginal hemorrhage, reversible increased bone marrow reticulin (reported as myelofibrosis),
Pharmion Presents Clinical Data Demonstrating Significant Survival ... - Dec 9, 2007
CNNMoney.com699-I: Hypermethylation of CXCR4 Promoter, and Its Reactivation by Hypomethylating Agent, in CD34 + Cells from Primary Myelofibrosis Patients (Abstract
Genoptix, Inc. Announces Availability of MPL W515 L/K Mutation ... - Dec 7, 2007
Reuters...are commonly associated with two myeloproliferative disorders, namely idiopathic myelofibrosis (IMF) and essential thrombocythemia (ET).
TargeGen Announces Planned Initiation of Clinical Trial of JAK2 ... - Dec 6, 2007
Reuters...including polycythemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF). In preclinical models of myeloproliferative diseases,
SABCS: Docetaxel (Taxotere) Outdoes Doxorubicin (Adriamycin) - Dec 14, 2007
MedPage Today,...more long-term toxicity, he said, including three fatalities -- one case each of congestive heart failure, myelodysplastic syndrome, and myelofibrosis.
Ipsogen launches the first quantitative mutation kit - Dec 14, 2007
Medical Laboratory World,PV (Polycythemia Vera, >90%) or ET (Essential Thrombocythemia, 70%); the lowest frequency was found in IMF patients (chronic Idiopathic MyeloFibrosis, 50%).
Pivotal Phase 3 NPLATE(TM) Study in Non-Splenectomized Patients ... - Dec 11, 2007
Financial News USA (press release),Exelixis, Inc. (NASDAQ: EXEL), recently reported phase 1 data from an ongoing phase 1 trial of XL019 in patients with myelofibrosis, a myeloproliferative
Top Scientists to Receive Prestigious Awards From the American ... - Dec 5, 2007
Earthtimes,...polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia, a discovery which has profound implications for potential therapies.
Gemin X Pharmaceuticals to Present Data on Obatoclax at American ... - Dec 3, 2007
PR-Inside.com (Pressemitteilung),Obatoclax Mesylate (GX15-070) Administered by a 24-h Continuous Infusion Every 2 Weeks to Patients with Chronic Idiopathic Myelofibrosis (CIMF).
Zokan found love at first sight, evermore - Nov 29, 2007
Milwaukee Journal Sentinel (subscription),20 of myelofibrosis, a bone marrow disease, with family members caring for her just as she had cared for her husband. Zokan was 77.
she took lead role when she had to - Nov 17, 2007
News & Observer,14 of complications from myelofibrosis, a bone marrow disorder. she was 80. where others wanted to vent, she craved action. she didn't indulge in
this ailment benefits from bleeding - Nov 18, 2007
Chicago Tribune,...which results in an overproduction of platelets, and primary myelofibrosis, which affects bone marrow. in 2007, another set of mutations,
wilmington drug company incyte announces wider loss - Nov 1, 2007
The News Journal,...progress in developing new drugs for hiv; diabetes; and psoriasis and myelofibrosis, a condition in which fibrous tumors develop in the bone marrow.
ipsogen launches the first quantitative jak2 v617f mutation kit - Nov 20, 2007
Medical News Today (press release),70%); the lowest frequency was found in imf patients (chronic idiopathic myelofibrosis, 50%). ipsogen is a molecular diagnostic company focused on the
casper family learns importance of bone marrow donors - Nov 8, 2007
Jackson Hole Star-Tribune,...which includes people from other countries. when ron depaolo was diagnosed with myelofibrosis, chelse depaolo said the family and doctors were hopeful.
business briefs - Nov 2, 2007
The News Journal,...diabetes; and psoriasis and myelofibrosis, a condition in which fibrous tumors develop in the bone marrow. pittsburgh-based pnc financial services group
incyte reviews positive proof-of-concept clinical results achieved ... - Nov 1, 2007
Business Wire (press release),...developed programs: our ccr5 antagonist for hiv, our jak inhibitor for myelofibrosis and psoriasis, and our 11beta-hsd1 inhibitor for type 2 diabetes.
Incyte Rises on Clinical Trial Data - Sep 26, 2007
Forbes,Banc of America analyst John J. Watkins said the results were all encouraging, but the drug is most likely to gain approval in myelofibrosis.
Incyte's Double Dose of Trial News - Sep 27, 2007
Motley FoolIncyte also reported on an oral version of INCB18424 to treat myelofibrosis, a bone marrow disease. The company is waiting until the American Society of
Incyte reports positive proof-of-concept results for INCB18424 ... - Sep 25, 2007
ReutersINCB18424 has now shown efficacy in these early studies when administered topically in psoriasis and when administered orally in myelofibrosis.
St. John Fisher star Lennox returns home to be with ailing mother - Oct 3, 2007
Rochester Democrat and Chronicle,Elaine was diagnosed in December with a chronic form of leukemia called myelofibrosis, in which the bone marrow is scarred and the patient's ability to
Incyte Reports Positive Proof-Of-Concept Results For INCB18424 And ... - Sep 25, 2007
RTT News,The company also said it has reached proof-of-concept clinical results in an ongoing dose-escalation Phase Ib/IIa trial in myelofibrosis using the oral
Carnival organisers back bone marrow drive - Aug 22, 2007
The Voice,Onyejekwe, a grandfather of four, is battling Myelofibrosis- a rare bone marrow disease, and is desperate to find a suitable donor after tests on his sister
Heard off the street: Benefit cuts test the mettle of men of steel - Aug 18, 2007
Pittsburgh Post Gazette,His wife Martha, 68, suffers from myelofibrosis, a blood disorder treated with $1800 weekly shots, $2400 in monthly pills and regular transfusions.
Warnex announces an exclusive licence with Ipsogen to market a ... - Aug 14, 2007
Canada NewsWire (press release),A high proportion of patients with myeloproliferative disorders (MPD; polycythemia vera, essential thrombocythemia, idiopathic myelofibrosis) carry a
September support groups - Aug 24, 2007
Journal Times,For people with a myeloproliferative disease including essential thrombocytosis, polycythemia vera and myelofibrosis, 1:30 pm, Sept.
Notting Hill carnival calls for bone marrow donors - 10 Aug 2007
24dash.com,He is facing up to his battle with a rare bone marrow disease, Myelofibrosis with courage and positivity. Cyril said: "More ethnic minority people need to
Myeloproliferative Disorders (Hematologic Malignancies) - Jul 17, 2007
Journal of American Medical Association (subscription),Formerly called "myeloid metaplasia," here it is designated as "idiopathic myelofibrosis, di Guglilmo's syndrome or erythroleukemia," and classified as a
Documentary to focus on hope - Jul 14, 2007
Portales News-Tribune,Gardels, who is pursuing a masters degree in religion at Eastern New Mexico University, has been battling a rare form of cancer, myelofibrosis,
Cancer tore through me. Still, you have to laugh - Aug 3, 2007
Scotsman,He has Myelofibrosis and it's a bugger because it means his red blood cells need to be topped up with units of blood every two weeks.
TargeGen, Inc. Closes $40M Series 'D' Financing Round - Jul 12, 2007
PR Newswire (press release),Additionally, TargeGen is developing TG101348, a Jak2 inhibitor, for the treatment of myeloproliferative diseases including myelofibrosis with myeloid
Umbilical Cord Blood Transplantation after a Reduced-Intensity ... - Jul 12, 2007
Cancer Consultants (press release),...and 35% had lymphoma with the remainder having chronic myeloid leukemia, myltiple myeloma, aplastic anemia, myelodysplastic syndrome and myelofibrosis.
Luck's Pilz fighting blood disorder - Mar 30, 2007
Burnett County Sentinel,Pilz apparently has Myelofibrosis. Medline Plus, a service of the US National Library of Medicine and the National Institute of Health describes
Out of the Gate: Celgene rises - Apr 4, 2007
BusinessWeekThe company's pipeline also includes treatments for sickle cell anemia, myelofibrosis, ischemia, psoriasis and cancer fatigue, along with anti-inflammatory
Gemin X Presents Positive Preclinical Data of GX15-070 in Infant ... - Apr 19, 2007
PipelineReview.com (press release),GX15-070 is also in Phase 2 clinical trials in patients with Hodgkin's Lymphoma, myelofibrosis with myeloid metaplasia, myelodysplastic syndrome,
The Ferrell family enjoys the weekend - Apr 1, 2007
Richmond Times Dispatch,Katherine was the donor when her mother had myelofibrosis, a form of leukemia, and needed a bone marrow transplant. Katherine donated her marrow to another
Bone Marrow Needed—You Can Help - Feb 8, 2007
13WHAM-TV,Myelofibrosis is rare, affecting less than 2 of 100000 people in the US When a person has myelofibrosis their marrow is scarring or getting damaged.
Arson suspected in fire - Feb 1, 2007
Youngstown Vindicator,Organizers said Clemente already is in Cleveland taking preliminary tests for the transplant, which he needs because he suffers from myelofibrosis,
Celgene Q4 2006 Earnings Call Transcript - Feb 1, 2007
Seeking Alpha,We have initiated a trial in myelofibrosis, are expanding our solid tumor studies and intend to initiate additional hematological studies this year.
Gerald L. Petersohn - Feb 14, 2007
Herald Times Reporter,12, 2007, at Aurora Bay Care, Green Bay, after a courageous battle with Myelofibrosis. He was born Dec. 1, 1948, in Manitowoc, son of Louis and Shirley
REV. KEN BAUMAN 1938 - 2007 Passed away peacefully, . . . - Feb 10, 2007
Waterloo Record,KEN BAUMAN 1938 - 2007 Passed away peacefully, following a courageous struggle with Myelofibrosis, on February 7, 2007, at St. Mary's General Hospital,
Growth Factor May Interfere With Normal Blood Cell Production - Feb 8, 2007
Science Daily (press release)Science Daily — Patients with so-called clonal myeloid disorders, such as myelofibrosis and some leukemias, often have bone marrow cells that are defective
Celgene Reported Exceptional Operating Performance Driven by ... - Feb 2, 2007
Drug Newswire (press release),...non-Hodgkin's lymphoma, myelofibrosis and hemoglobinopathies. For the full-year period, the Company incurred adjusted R&D expenses of $245.9 million.
JAK2 Exon 12 Mutations in Polycythemia Vera and Idiopathic ... - Jan 31, 2007
New England Journal of Medicine (subscription),...of the Janus kinase (JAK) 2 gene (JAK2), is often present in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis.
Gemin X Initiates Phase 1/2 Combination Trials with GX15-070 in ... - Jan 31, 2007
PharmaLive.com (press release),Gemin X recently initiated Phase 2 clinical trials with GX15-070 in patients with Hodgkin's Lymphoma and in myelofibrosis with myeloid metaplasia.
TargeGen Selects Jak2 Inhibitor Lead (TG101348) for Clinical ... - Jan 7, 2007
Drug Newswire (press release),These include the diseases polycythemia vera, essential thrombocythemia (ET) and myelofibrosis with myeloid metaplasia (MMM).
NEUMEISTER, Earl Roy - After a courageous battle with . . . - Dec 28, 2006
Waterloo Record,...(Dec 28, 2006) -- NEUMEISTER, Earl Roy - After a courageous battle with myelofibrosis, Earl passed away on December 27, 2006, at Lisaard House in Cambridge.
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