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(2º) Financial Results  -  Mar 20, 2008
InfoBolsa,Examples of cancer-associated client proteins of Hsp90 include c-KIT in gastrointestinal stromal tumors, epidermal growth factor receptor (EGFR) in lung

Sutent® Has Activity in Patients with Advanced Non–Small Cell Lung ...  -  Mar 6, 2008
Cancer Consultants,Sutent is approved for the treatment of advanced renal cell cancer, as well as for the treatment of gastrointestinal stromal tumors after disease

Pezcoller Foundation-AACR International Award For Cancer Research ...  -  Mar 4, 2008
BioResearch Online (press release),...kinase inhibitor, SU1128/SUTENT which was approved by the FDA in 2006 for the treatment of kidney carcinoma and gastrointestinal stromal tumors.

NMBio Announces the 2008 Board of Directors  -  Feb 29, 2008
Earthtimes,...lead to the introduction of Glivec, the first specific treatment of chronic myelogenous leukemia (CML) and gastrointestinal stromal tumors (GIST).

Infinity and MedImmune Announce Approval for Generic Name for ...  -  Feb 4, 2008
CNNMoney.com...of a variety of solid tumor cancers, including gastrointestinal stromal tumors, non-small cell lung cancer, and hormone resistant prostate cancer.

Worldwide Study Shows No Differences in Sunitinib Effectiveness ...  -  Jan 25, 2008
DG NewsMetastatic or unresectable gastrointestinal stromal tumors are usually treated with imatinib (Gleevec), but 12% to 14% of patients have initial resistance

Investigational Motesanib Provides Clinical Benefit in Phase 2 ...  -  Jan 27, 2008
DG News...[Presentation title: Phase II Study of Motesanib Diphosphate (AMG 706) in Japanese Patients With Advanced Gastrointestinal Stromal Tumors (GISTs) Who

Infinity Highlights Broad Expansion of Hsp90 Clinical Program and ...  -  Feb 13, 2008
Primenewswire (press release),...the company's lead heat shock protein 90 (Hsp90) inhibitor, in patients with gastrointestinal stromal tumors (GIST) and other soft tissue sarcomas;

Sunitinib linked to more heart failure than previously known  -  Feb 15, 2008
TheHeart.Org,The drug, which is used to treat renal-cell carcinoma and gastrointestinal stromal tumors, has been linked to more heart failure than previously reported.

Autologous Intestinal Transplant Saves the Day for Gardner's ...  -  Feb 7, 2008
MedPage Today,While transplantation would thus never be considered for malignant tumors, he suggested the procedure could be used for gastrointestinal stromal tumors

97% Survival at 3 Years in Patients Receiving Adjuvant Imatinib ...  -  Jan 27, 2008
DG NewsBy Ed Susman ORLANDO, Florida - January 26, 2008 - Patients undergoing surgery for gastrointestinal stromal tumors (GISTs) who receive imatinib mesylate

ASCO GI: Adjuvant Imatinib Boosts GIST Recurrence-Free Survival  -  Jan 28, 2008
MedPage Today,28 -- Overall survival at three years was 97% in the first trial of imatinib (Gleevec) as adjuvant therapy for gastrointestinal stromal tumors, according to

ASCO GU: Sunitinib Cardiotoxicity Unexpectedly High in Real-World Use  -  Feb 13, 2008
MedPage Today,13 -- For patients with kidney cancer or gastrointestinal stromal tumors (GIST) treated with sunitinib (Sutent), the heart failure risk in real-world use

ASCO GI: Investigational Second-Line GIST Agent Shows Activity  -  Jan 29, 2008
MedPage Today,29 -- A new candidate for imatinib (Gleevec)-resistant gastrointestinal stromal tumors (GIST), the investigational agent motesanib, showed activity for

Research and Markets: Infinity Pharmaceuticals Inc: Premium ...  -  Feb 1, 2008
Business Wire (press release),...wide range of diseases in the therapeutic area of oncology, including gastrointestinal stromal tumors, multiple myeloma and non-small-cell lung cancer.

ASCO GI: Serum Imatinib (Gleevec) Levels Predict GIST Response  -  Jan 25, 2008
MedPage Today,...clinical responses in patients with gastrointestinal stromal tumors (GIST), but proper initial doses were unpredictable, a researcher reported here.

New Thai Minister May Review Compulsory Licences On Cancer Drugs  -  Feb 8, 2008
Intellectual Property Watch,Since then Novartis, which holds the patent on imatinib for treating leukemia and gastrointestinal stromal tumors and markets it as Glivec, has agreed to

ASCO GI: Molecular Clues Help Refine Kinase Inhibitor Strategy for ...  -  Jan 28, 2008
MedPage Today,28 -- In the post-imatinib (Gleevec) era, treatment of gastrointestinal stromal tumors has shifted from serial surgeries to refinement of kinase inhibitor

Search By Symbol  -  Jan 23, 2008
RTT News,Revenues from Sutent, which is used treatment of advanced kidney cancer and gastrointestinal stromal tumors, surged 75% to $182 million.

Pfizer Reports Fourth-Quarter and Full-Year 2007 Results and 2008 ...  -  Jan 23, 2008
Centre Daily Times,In the fourth-quarter 2007, revenues from Sutent, an important medicine for the treatment of advanced kidney cancer and gastrointestinal stromal tumors,

New Cancer Drug Tied to Heart Problems  -  Dec 13, 2007
Forbes,..."This drug is lifesaving for people with metastatic, gastrointestinal stromal tumors," she added. But it is important for both doctors and patients to be

Constant Monitoring for Cardiovascular Events Mandated During ...  -  Dec 26, 2007
Medi News Direct,...the first anticancer drug simultaneously approved for two different indications, renal cell carcinoma (RCC) and gastrointestinal stromal tumors (GIST).

Major Clinical Cancer Advances in 2007  -  Dec 27, 2007
Medscape (subscription)Imatinib (Gleevec, Novartis) increases recurrence-free survival in patients with gastrointestinal stromal tumors. Aspirin use promising for prevention of

Pfizer cancer drug Sutent linked with heart risks  -  Dec 13, 2007
Guardian Unlimited,She and colleagues reviewed all heart events in 75 adults with gastrointestinal stromal tumors that had spread. They had been enrolled in a clinical trial

Sunitinib Proves Cardiotoxic in GI Tumor Treatment  -  Dec 14, 2007
MedPage Today,14 -- Treatment of gastrointestinal stromal tumors with sunitinib (Sutent) led to cardiac events in 11% of patients and to clinically relevant reductions in

Infinity and MedImmune Initiate Phase 2 Trial of IPI-504 to Assess ...  -  Dec 19, 2007
CNNMoney.com1 clinical trials in patients with metastatic and/or unresectable gastrointestinal stromal tumors and patients with advanced non-small cell lung cancer.

New imatinib formulation cuts cardiac toxicity  -  Dec 10, 2007
TheHeart.Org,The anticancer activity of the reengineered agent, called WBZ-4, was instead preserved against gastrointestinal stromal tumors in both in vitro and in vivo

Tasigna Gains European Approval For Patients With A Life ...  -  Dec 3, 2007
Medical News Today (press release),Separately, a Phase III program has been launched involving the use of Tasigna in patients with gastrointestinal stromal tumors (GIST) who are resistant or

Scientists Reveal Role Of Gene In Sensitivity To Thermal Pain  -  Dec 6, 2007
Science Daily (press release)...a few years ago revolutionized the treatment of breast cancer, leukemias and gastrointestinal stromal tumors, but also can apparently alleviate pain.

Targeted cancer drug poses heart risk: Sutent is the latest linked ...  -  Dec 17, 2007
Trading Markets (press release),They collected heart function and blood pressure data on patients with gastrointestinal stromal tumors throughout a two-year trial of Sutent,

Sunitinib Treatment Requires Close Monitoring for Heart Damage  -  Dec 14, 2007
Cancerpage.com,2007 (Reuters Health) - Treatment with sunitinib, a tyrosine kinase inhibitor used for metastatic renal cell cancer and gastrointestinal stromal tumors

Gleevec effective against leukemia.  -  Dec 10, 2007
Earthtimes,Gleevec is approved for the treatment of gastrointestinal stromal tumors, pediatric chronic myeloid leukemia, as well as five additional rare cancers.

Targeted cancer pill Gleevec improves outcomes for kids with leukemia  -  Dec 10, 2007
Thaindian.com,Gleevec has also been approved for the treatment of gastrointestinal stromal tumors, pediatric CML, as well as five additional rare cancers. (ANI)

Anti-Cancer Drug Made More Specific By Modification  -  Dec 4, 2007
Medical News Today (press release),Glivec in Europe and Australia) is used to treat various cancers, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs).

Tasigna(R) gains European approval for patients with a life ...  -  27 Nov 2007
CNNMoney.comSeparately, a Phase III program has been launched involving the use of Tasigna in patients with gastrointestinal stromal tumors (GIST) who are resistant or

infinity and medimmune initiate phase 2 clinical trial of ipi-504 ...  -  Nov 13, 2007
CNNMoney.com...ipi-504 is currently being evaluated in the expansion phase of an ongoing phase 1 trial in patients with metastatic gastrointestinal stromal tumors and soft

infinity announces hedgehog pathway inhibitor agreement with ...  -  Nov 12, 2007
CNNMoney.com...has demonstrated evidence of biological activity in both gastrointestinal stromal tumors (gist) and in non-small cell lung cancer (nsclc). the companies

pharma market: first out of gate, nexavar loses ground  -  Nov 8, 2007
CNNMoney.com30 were $ 618 million , with third-quarter sales up 140% at $151 million . these include sutent's approved use to treat gastrointestinal stromal tumors.

for the record  -  Nov 19, 2007
Springfield State Journal Register,2, at the firefighters lake club, 940 west lake shore drive. brittin has fought gastrointestinal stromal tumors for more than nine years. his family has

synta pharmaceuticals reports third-quarter 2007 financial results  -  Nov 13, 2007
Genetic Engineering News (press release),...these client proteins. examples of cancer-associated client proteins of hsp90 include c-kit in gastrointestinal stromal tumors, epidermal growth factor

infinity, medimmune begin trial of ipi-504  -  Nov 14, 2007
FDA news (subscription),...candidate also is being evaluated in the expansion phase of a phase i trial in patients with metastatic gastrointestinal stromal tumors and soft tissue

thailand: latest talks with patent owners of cancer drugs show ...  -  Nov 5, 2007
Intellectual Property Watch,...which produces imatinib for treating leukemia and gastrointestinal stromal tumors and letrozole for breast cancer and markets them as glivec and femara

novartis: tasigna receives its first us approval for leukemia  -  Oct 30, 2007
Pharmaceutical Business Review...eu and japan for the treatment of all phases of ph+ cml and is approved in the us and eu for gastrointestinal stromal tumors. the incidence of gleevec

Novartis Q3 Profit Surges On Divestment Gains; Plans 1260 Job Cuts ...  -  Oct 18, 2007
RTT News,Gleevec/Glivec, a therapy for chronic myeloid leukemia, or CML, and gastrointestinal stromal tumors, generated total sales of $783 million in the quarter,

Novartis delivers record earnings in first nine months of 2007 ...  -  Oct 17, 2007
Market Wire (press release)Gleevec/Glivec (USD 2.2 billion, +14% lc), a targeted therapy for certain forms of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST)

New City woman raises research funds for rare cancer  -  Oct 12, 2007
The Journal News / Lohud.com,Tomorrow, for the seventh year, she is organizing a walk around Rockland Lake to raise research funds for gastrointestinal stromal tumors, known as GIST,

Tasigna Recommended for European Approval to Treat Rare Form of ...  -  Sep 21, 2007
PharmaLive.com (press release),A registration study is also underway in certain patients with gastrointestinal stromal tumors (GIST). The CHMP decision was based on an open-label Phase II

Science: Healthy Victory  -  Sep 30, 2007
The Columbian,Paul is among about 600 participants in the study, which is investigating the effects of Gleevec on gastrointestinal stromal tumors.

Thailand may override patents on some cancer drugs  -  Sep 24, 2007
Inquirer.net,Imanitib, marketed by Novartis as Gleevec in the United States and Glivec in Europe, is used to treat leukaemia and gastrointestinal stromal tumors.

OHSU's Druker honored for cancer work  -  Oct 9, 2007
The Oregonian - OregonLive.com,The drug is now standard treatment for several less-common cancers, including chronic myeloid leukemia and gastrointestinal stromal tumors, and has greatly

Hepatoma-derived growth factor predicts GI tumor outcome  -  Sep 5, 2007
Medicexchange (press release),Expression of hepatoma-derived growth factor is elevated in high-risk gastrointestinal stromal tumors, Taiwanese researchers report in the September 1st

A Novel Tyrosine-Kinase Selective Inhibitor, Sunitinib, Induces ...  -  Sep 6, 2007
Journal of Clinical Endocrinology and Metabolism,Objective: Our objective was to evaluate the effect of sunitinib on thyroid function in 24 patients with gastrointestinal stromal tumors.

Genetics of Carney Triad: Recurrent Losses at Chromosome 1 but ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Context: Carney triad (CT) describes the association of paragangliomas (PGLs) with gastrointestinal stromal tumors (GISTs) and pulmonary chondromas.

Bikers Pedal 1000 Miles For Cancer Cure  -  Aug 6, 2007
KOIN.com,...for a friend or family member suffering from what was one of the deadliest cancers: a rare tumor known as gastrointestinal stromal tumors, or GIST.

Combined Imaging Sharpens View of Tumors  -  Aug 1, 2007
CancerWiseOne example involves the use of FDG to trace tumors during PET scans, to evaluate the early effects of Gleevec® in treating gastrointestinal stromal tumors

Q&A: Targeted Gleevec Therapy for GIST  -  Aug 1, 2007
CancerWiseDoctors know what drug to use in treating a patient with gastrointestinal stromal tumors (GIST). Now they know how much of this drug to prescribe,

Pfizer Says Growth in Phase II Portfolio Supports Goal of Tripling ...  -  Aug 6, 2007
Business Wire (press release),Sutent was launched late last year to treat renal cell carcinoma and gastrointestinal stromal tumors. Pfizer’s Phase III study using Sutent in patients with

Novartis's Tasigna gets first approval  -  Jul 24, 2007
Reuters..."A registration study is already underway in patients with gastrointestinal stromal tumors (GIST), which can also be treated with Glivec in certain

Medical Specialist looks to treat conditions like fibromyalgia ...  -  Jul 19, 2007
Al-Bawaba,...other priority reviews included Sutent for advanced kidney cancer and gastrointestinal stromal tumors and Champix for smoking cessation.

Novartis Delivers Strong Performance in First Half of 2007 (H1 ...  -  Jul 16, 2007
Genetic Engineering News (press release),...+14% lc), a targeted therapy used in patients with certain forms of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST) as well as

Studies of Drug Resistance May Lead to Individual Therapy for Rare ...  -  Jul 2, 2007
PR Newswire (press release),Gastrointestinal stromal tumors are rare cancers of the gastrointestinal tract. If detected early, GIST can be treated by surgery.

Pfizer’s Lyrica Receives FDA Approval for Fibromyalgia  -  Jun 22, 2007
PharmaLive.com (press release),...other priority reviews included Sutent for advanced kidney cancer and gastrointestinal stromal tumors and Chantix for smoking cessation.

Hologic To Buy BioLucent And MammoPad Breast Cushion Business ...  -  Jun 21, 2007
RTT News,Pfizer's other priority reviews include Sutent for advanced kidney cancer and gastrointestinal stromal tumors, Chantix for smoking cessation and Lyrica's

Novartis Cancer Drug Boosts Survival After Intestinal Surgery  -  04 Jun 2007
Wall Street Journal...the risk of the return of a particular type of intestinal cancer when given to patients after surgery to remove gastrointestinal stromal tumors or GIST.

Infinity and MedImmune Announce Updated Data On Ipi-504 to be ...  -  May 31, 2007
PharmaLive.com (press release),Inc. (Nasdaq:MEDI) today announced that interim clinical data on IPI-504 in a Phase I trial in patients with gastrointestinal stromal tumors (GIST) and

Pitt Researchers Receive Funding to Improve Treatment of  -  May 14, 2007
WebWire (press release),...received $25000 from the GIST Cancer Research Fund – a patient driven organization that funds research on gastrointestinal stromal tumors, or GISTs.

Pfizer, Bristol to highlight cancer drugs at doctor meeting  -  May 30, 2007
MarketWatchLast year it started selling Sutent as a treatment for advanced kidney cancer and gastrointestinal stromal tumors. It's pursuing new uses for Sutent and is

Gleevec available to patients in post-surgical GIST study  -  Apr 15, 2007
News-Medical.net,Gastrointestinal stromal tumors (GIST) belong to a group of cancers known as soft tissue sarcomas that usually arise from the intestinal tract,

Positive Results Prompt US National Cancer Institute to Make ...  -  Apr 12, 2007
PR Newswire (press release),Gleevec found to dramatically reduce the risk of cancer returning after surgery for Kit-positive gastrointestinal stromal tumors (GIST) - Patients receiving

Cancer Drug Trial Halted For Positive Results  -  Apr 16, 2007
eMaxHealth.com,In addition to preventing the recurrence of gastrointestinal stromal tumors, imatinib appeared to have few side effects, among them nausea, diarrhea and

Novartis Pharmaceuticals (NVS): Positive Results Prompt US ...  -  Apr 12, 2007
StreetInsider.com (subscription),American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following

Gleevec proves adept at halting cancer's return  -  Apr 18, 2007
OregonLive.com,The findings, announced last week, should make Gleevec standard treatment for people with gastrointestinal stromal tumors, or GIST, a stomach and intestine

Rare stomach cancer stopped by Gleevec  -  Apr 17, 2007
TopCancerNews.com,The promise of Gleevec should make it standard treatment for people with gastrointestinal stromal tumors (GIST), a stomach and intestine cancer diagnosed in

Infinity and MedImmune to Present Preclinical Data From Study of ...  -  Apr 10, 2007
PharmaLive.com (press release),...intravenous formulation in two disease-focused clinical trials involving patients with gastrointestinal stromal tumors (GIST) and NSCLC.

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