This page contains recent news articles, when available, and an overview of but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Background information on

Keryx says diabetic nephropathy drug misses primary endpoint in ...  -  Mar 10, 2008
CNNMoney.comThe drug was designed to treat diabetic nephropathy. The company said the results for patients tested were similar to the results for patients on a placebo.

Uric Acid May Provide Early Clues To Diabetic Kidney Disease  -  Mar 20, 2008
Science Daily (press release)None of the patients had higher levels of albumin (albuminuria) representing more advanced diabetic nephropathy. Nevertheless, one in five had some

Keryx's Phase 3 Clinical Trial Of Sulonex For Diabetic Nephropathy ...  -  Mar 7, 2008
Trading Markets (press release),Inc. (KERX | news | PowerRating | PR Charts ) announced that Phase 3 clinical trial of Sulonex for the treatment of diabetic nephropathy failed to meet

Keryx Biopharma's Phase 3 Trial Of Sulonex For Diabetic ...  -  Mar 7, 2008
RTT News,3/7/2008 8:22:30 PM Keryx Biopharmaceuticals, Inc. (KERX) announced that Phase 3 clinical trial of Sulonex for the treatment of diabetic nephropathy failed

GlaxoSmithKline to Pay Pharmacopeia $5M  -  Mar 18, 2008
CNNMoney.comPharmacopeia is developing small-molecule treatments for high blood pressure, diabetic nephropathy, muscle wasting, inflammation and respiratory disease.

Sulonex from Keryx: Unlikely Phase III Success  -  Feb 27, 2008
Seeking Alpha,Though its mechanism of action in diabetic nephropathy is uncertain, it is hypothesized that sulodexide â€“ a gylcosaminoglycan [GAG] â€“ restores the anionic

Keryx Biopharma shares dive on failed late-stage study  -  Mar 10, 2008
Therapeutics Daily (subscription) (press release),On March 7, Keryx said a late phase clinical trial for its drug candidate Sulonex, designed to treat diabetic nephropathy, failed to meet the main goal of

Clinical trial fails for Keryx Biopharmaceuticals  -  Mar 10, 2008
SmallCapInvestorDiabetic nephropathy is a progressive kidney disease that results in an increase in blood pressure (hypertension) and fluid retention in the body.

Types of Chronic Complications-Diabetes  -  Feb 26, 2008
American Chronicle,In a patient with Type 1 diabetes, diabetic nephropathy typically progress through five stages. Stage I Stage I, which occurs soon after the onset of

Keryx Takes Major Hit as Sulonex Fails Phase III.  -  Mar 11, 2008
Therapeutics Daily (subscription) (press release),Keryx BioPharmaceuticals Inc. said its Phase III study of Sulonex for diabetic nephropathy failed to meet its primary endpoint, causing the company's stock

Uric acid may predict kidney function in diabetics  -  Mar 17, 2008
Food Consumer,By David Liu, Ph. D. MONDAY March 17, 2008 (Foodconsumer.org) -- Uric acid in the blood may be a better indicator than albumin in the urine for the loss of

Dynamis Therapeutics, Inc. Discovers RAGE Inhibitor  -  Mar 17, 2008
Earthtimes,...develops products that treat chronic inflammatory conditions and accelerated aging diseases such as diabetic nephropathy and retinopathy.

Study: Nerve growth factor concentrations may help evaluate ...  -  Mar 5, 2008
OSN SuperSite (subscription),...â€œ[Nerve growth factor] levels correlated well with diabetes duration, HbA1c, and blood sugar levels and diabetic nephropathy,â€? they said.

Novel Discovery Could Lead To Much-needed Kidney Failure Treatment  -  Mar 15, 2008
Science Daily (press release)Collectively, the observations made in the Einstein study offer strong evidence that aberrant Notch signaling is also involved in diabetic nephropathy (DNP)

DiObex and Camurus Sign License Agreement for the Development of ...  -  Mar 18, 2008
Earthtimes,...single enantiomer of ketoconazole that is a novel cortisol synthesis inhibitor in development for type 2 diabetes mellitus and diabetic nephropathy.

Pharmacopeia Initiates Second Phase 2 Hypertension Study With  -  Mar 4, 2008
Pharmaceutical Online (press release),...angiotensin (AII) and endothelin (ET1) receptor antagonist that is being developed as a potential treatment for hypertension and diabetic nephropathy.

Renal Decline More Rapid in HIV Patients  -  Feb 26, 2008
Renal and Urology News,Just like with diabetic nephropathy, small amounts of albumin predict the development of big amounts of protein down the road.â€? In diabetic nephropathy

McDonald's, Nationwide Get a Boost  -  Mar 10, 2008
Wall Street Journal...after the company released disappointing data from a trial of Sulonex, its treatment for diabetic nephropathy, a kidney disease caused by diabetes.

Movers: MBIA, Countrywide, Virgin Media, Fannie Mae  -  Mar 10, 2008
BusinessWeekKeryx Biopharmaceuticals (KERX) announces top-line results from its SUN-MICRO Phase 3 clinical trial of Sulonex for treatment of diabetic nephropathy,

Out of the Gate: Keryx Plunges  -  Mar 10, 2008
CNNMoney.comOn Friday, the New York-based company said Sulonex was not more effective than a placebo in treating diabetic nephropathy, or kidney disease brought on by

Keryx Biopharma says SUN-MICRO Phase 3 trial of Sulonex fails to ...  -  Mar 9, 2008
CNNMoney.com...said the SUN-MICRO Phase 3 clinical trial of Sulonex for the treatment of diabetic nephropathy failed to meet the primary endpoint of the study.

Pharmacopeia to Receive $5 Million Payment from GlaxoSmithKline  -  Mar 18, 2008
Earthtimes,Phase 1 development addressing multiple indications including hypertension, diabetic nephropathy, muscle wasting, inflammation and respiratory disease.

BUYINS.NET: JMBA, KERX, STEN, TELK, JYHW, TMLN Have Also Been ...  -  Mar 17, 2008
Trading Markets (press release),The company's endocrine/renal products include Sulonex, a Phase III and Phase IV clinical stage product for the treatment of diabetic nephropathy;

New Study may Pave the Way for Kidney Failure Treatment  -  Mar 13, 2008
MedIndia,The researchers' observation during the study offers strong evidence that aberrant Notch signaling plays a role in diabetic nephropathy (DNP) and focal

HMC plans a slew of events to mark World Kidney Day  -  Mar 11, 2008
Gulf Times,...â€˜Cadaver transplants in Qatarâ€™ (Dr Hatem Elshobaki), and â€˜Diabetic nephropathyâ€™ (Dr Mohamed Amin). Information booths are to be set up at all hospitals,

Unusual 11 Mid-Day Movers 3/10: TCM, NFS, IOM Higher; KERX, TMA ...  -  Mar 10, 2008
StreetInsider.com (subscription),...(Nasdaq: KERX) 86.9% LOWER; announced top-line results from its SUN-MICRO Phase 3 clinical trial of Sulonex for the treatment of diabetic nephropathy.

Keryx Joins Biotech Zombie Ranks (KERX)  -  Mar 10, 2008
24/7 Wall St.,The company announced that top-line results from its SUN-MICRO Phase III clinical trial of Sulonex for the treatment of diabetic nephropathy have failed to

3/10/2008 8:34:39 AM Origin Agritech (SEED) rose in pre-market ...  -  Mar 10, 2008
RTT News,Keryx Biopharmaceuticals announced that SUN-MICRO Phase 3 clinical trial of Sulonex (sulodexide), for the treatment of diabetic nephropathy, failed to meet

White Mountains Signs Exchange Agreement With Berkshire Hathaway ...  -  Mar 10, 2008
RTT News,Inc. (KERX) announced that SUN-MICRO Phase 3 clinical trial of Sulonex (sulodexide), for the treatment of diabetic nephropathy, failed to meet the

Keryx drug fails FDA trial  -  Mar 9, 2008
Globes,...it will find it difficult to recover, with the failure of Phase III trials for its drug, Sulonex (sulodexide) for the treatment of diabetic nephropathy.

Keryx Biopharmaceuticals Announces that the SUN-MICRO Phase 3 ...  -  Mar 7, 2008
Earthtimes,Inc. today announced top-line results from its SUN-MICRO Phase 3 clinical trial of Sulonex (sulodexide) for the treatment of diabetic nephropathy.

Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year ...  -  Feb 25, 2008
PharmaLive.com (press release),...a first-in-class, oral heparinoid compound for the treatment of diabetic nephropathy, a life-threatening kidney disease caused by diabetes.

Seek eye tests to avoid diabetic retinopathy  -  Feb 18, 2008
New Straits Times,On diabetic nephropathy which affects the kidneys, she said 15000 Malaysians were on haemodialysis last year, with the number on the rise.

Signs and Symptoms of Diabetic Nephropathy  -  Jan 22, 2008
American Chronicle,By Robert Baird In the early stages of diabetic nephropathy, a patient usually doesn't experience symptoms. Typically, symptoms occur when her glomerular

Keryx Biopharmaceuticals Completes SUN-MICRO Phase 3 Pivotal Trial  -  Feb 11, 2008
PR Newswire (press release),A variety of members of this chemical family have been shown to decrease pathological albumin excretion in diabetic nephropathy in humans.

Synvista Therapeutics to Present at the 10th Annual BIO CEO ...  -  Feb 6, 2008
FOXBusiness...and/or ongoing Phase 2 initiatives for ALT-2074 in cardiovascular diseases and psoriasis, and alagebrium in heart failure and diabetic nephropathy.

Pharmacopeia Nominates Novel Chemokine Receptor Antagonist for ...  -  Feb 11, 2008
PharmaLive.com (press release),Pharmacopeia's internal clinical pipeline consists of PS433540 (DARA) for hypertension and diabetic nephropathy and PS178990 (SARM) for muscle wasting

GSK declines option on failed Exelixis drug  -  Jan 22, 2008
Milwaukee Business Journal,...a possible treatment for diabetic nephropathy -- with Exelixis, either by itself or through some new agreement with another company.

What are the chronic complications of diabetes?  -  Jan 27, 2008
TamilStar.com,Kidney damage from diabetes is called diabetic nephropathy. The onset of kidney disease and its progression is extremely variable.

Early Multifactorial Intervention Key in Diabetes  -  Feb 8, 2008
Medscape (subscription)Patients with type 2 diabetes have increased rates of complications related to cardiovascular disease and diabetic nephropathy, retinopathy, and neuropathy.

Big Money Steers Clear of Biotech  -  Feb 14, 2008
TheStreet.comThe company presented Monday, announcing the completion of a pivotal phase III study of its diabetic nephropathy drug Sulonex. The data from this important

Pharmacopeia to Present at The Roth 20th Annual OC Growth Stock ...  -  Feb 13, 2008
FOXBusinessPhase 1 development addressing multiple indications including hypertension, diabetic nephropathy, muscle wasting, inflammation and respiratory disease.

Sanofi-aventis' SoloSTAR(R) Insulin Pen for Lantus and Apidra ...  -  Feb 14, 2008
PR Newswire UK (press release),Diabetic nephropathy (kidney disease), which may result in total kidney failure and in the need for dialysis or kidney transplant.

Diabetes Glossary of Terms  -  Jan 27, 2008
TamilStar.com,Diabetic nephropathy: The kidney disease associated with long-standing diabetes. Diabetic nephropathy is also called Kimmelstiel-Wilson disease (or

Healthcare Providers Direct, Inc. Announces First Accurate and ...  -  Feb 1, 2008
FOXBusiness...recommends a microalbumin urine test for people with Type 2 diabetes: first at diagnosis and then yearly for diabetic nephropathy (kidney disease).

Exelixis Announces Full Year and Fourth Quarter 2007 Financial Results  -  Feb 14, 2008
Earthtimes,Based on encouraging data from a subgroup analysis, the compound may nevertheless have potential to benefit patients with diabetic nephropathy and we are

Keryx Biopharmaceuticals Announces Upcoming Corporate Presentations  -  Feb 5, 2008
FOXBusiness...a first-in-class, oral heparinoid compound for the treatment of diabetic nephropathy, a life-threatening kidney disease caused by diabetes.

DiObex, Inc. to Present at Merrill Lynch Global Healthcare Conference  -  Feb 5, 2008
FOXBusiness...single enantiomer of ketoconazole that is a novel cortisol synthesis inhibitor in development for type 2 diabetes mellitus and diabetic nephropathy.

Hot and Not at Exelixis  -  Jan 23, 2008
Motley Fool...word that partner GlaxoSmithKline (NYSE: GSK) was rejecting its option to take over development of Exelixis's diabetic nephropathy drug candidate XL784.

GlaxoSmithKline rejects kidney disease drug  -  Jan 21, 2008
Bizjournals.com,...an option to develop XL784, a drug that failed a phase II trial in patients with diabetic nephropathy. The kidney disease is common in diabetics.

Diabetes Increasingly Common in Older Adults  -  Jan 28, 2008
MedPage Today,Renal disease rates increased with about a doubling in rate of diabetic nephropathy and chronic renal failure in the first year after diagnosis (54 and 41

Options Update: Keryx Biopharmaceuticals (KERX), Progenics ...  -  Jan 30, 2008
The Options InsiderKERX lead compound, Sulonex (sulodexide oral gelcap), is a first-in-class, oral heparinoid compound for the treatment of diabetic nephropathy,

Josephine Briggs, MD, Named Director of NCCAM  -  Jan 25, 2008
NPIcenter (press release),Her research interests include the renin-angiotensin system, diabetic nephropathy and the effect of antioxidants in kidney disease.

Characteristics of Patients Prescribed Angiotensin-Converting ...  -  29 Dec 2007
Abkhazia,...[9] Studies of blockade of the RAAS in patients with type 1 diabetes and diabetic nephropathy, and patients with type 2 diabetes and microalbuminuria,

Sulodexide Data Safety Monitoring Committee Completes Additional ...  -  Dec 5, 2007
CNNMoney.comA variety of members of this chemical family have been shown to decrease pathological albumin excretion in diabetic nephropathy in humans.

Keryx: Panel says drug candidate doesn't raise safety concerns  -  Dec 6, 2007
ReutersDiabetic nephropathy is a complication of diabetes in which the kidneys are progressively damaged. (Reporting by Neha Pathania in Bangalore;

Pharmacopeia Announces Additional Positive Findings from Phase 1 ...  -  Dec 3, 2007
CNNMoney.com...and related disorders such as diabetic nephropathy," stated Rene Belder, MD, Pharmacopeia's Vice President of Clinical and Regulatory Affairs.

Pharma Blog Watch  -  Dec 16, 2007
FDA news (subscription),...independent data safety monitoring committee raising no safety concerns for a Phase III trial of Sulonex, a treatment for diabetic nephropathy.

Kerx Biopharma Says Sulodexide Phase 3 Study Completes Additional ...  -  Dec 5, 2007
RTT News,...or DSMC, completed additional review of the ongoing Phase 3 trial of the company's lead drug candidate Sulonex to treat diabetic nephropathy.

Keryx Gets OK for Sulonex Drug Study  -  Dec 6, 2007
CNNMoney.com...the company's lead drug candidate under development as a treatment for diabetic nephropathy, a long-term complication of diabetes that damages the

Keryx: Data safety committee recommends no alteration for Sulonex ...  -  Dec 6, 2007
CNNMoney.comSulonex is Keryx's lead drug candidate under development as a treatment for diabetic nephropathy. Keryx said, after completing a review of all safety and

Pharmacopeia says Phase I study for PS433540 shows additional ...  -  Dec 3, 2007
CNNMoney.com...novel compound as a new therapeutic option for patients affected by hypertension and related disorders such as diabetic nephropathy,' Pharmacopeia said.

Another convict in Ninoy Aquino assassination eyes parole  -  Dec 17, 2007
Inquirer.net,It said he has been suffering from "diabetes mellitus type 2, hypertension, diabetic retinopathy, diabetic nephropathy and diabetic neuropathy/gastropathy.

Kidney patient in appeal for funds  -  Dec 11, 2007
Gulf Times,Moosa, who worked as a driver for the company, has been diagnosed with end-stage renal disease and diabetic nephropathy by the Hamad hospital.

Keryx Biopharmaceuticals, Inc. Announces Poster Presentations ...  -  Dec 7, 2007
Reuters...a first-in-class, oral heparinoid compound for the treatment of diabetic nephropathy, a life-threatening kidney disease caused by diabetes.

Thursday's Health Winners & Losers  -  Dec 6, 2007
TheStreet.com...committee watching a phase III trial for diabetic nephropathy treatment Sulonex found no reason to recommend alternation or termination of the study.

Phase I Results for ISF402  -  Dec 5, 2007
Sydney Morning Herald,...for diabetic nephropathy and atherosclerosis Diabetes is a major metabolic disease now regarded as reaching epidemic proportions in the developed world.

Receptor protein appears to be key in breakdown of kidney filtration  -  Dec 19, 2007
EurekAlert (press release),...which may represent a novel therapy for kidney diseases such as diabetic nephropathy and focal segmental glomerulosclerosis,â€? adds Changli Wei, MD, PhD,

Alternative medicine: Rhubarb  -  Dec 11, 2007
PRESS TV,Rhubarb is an effective diuretic and used to treat kidney stones, diabetic nephropathy, chronic renal failure, pregnancy-induced hypertension, gout,

Small Cap Stocks to Watch - RIGL, KERX, KKD, GNMT  -  Dec 6, 2007
TransWorldNews (press release),...the Company's lead drug candidate under development as a treatment for diabetic nephropathy, recently met to evaluate the data from the ongoing Phase 3

Durect Announces Primary Endpoint Of Phase III Clinical Trial ...  -  Dec 6, 2007
RTT News,Independent Data Safety Monitoring Committee, on ongoing Phase 3 trial of its diabetic nephropathy drug candidate, Sulonex or sulodexide oral gelcaps.

Corning Board Approves 5-year Capital Expenditure Plan To Co ...  -  Dec 5, 2007
RTT News,Sulonex is the company's lead drug candidate under development as a treatment for diabetic nephropathy. The company anticipated that the last patient will

Discover Financial To Record Charge For Goldfish Business; To ...  -  Dec 3, 2007
RTT News,...a dual-acting angiotensin and endothelin receptor antagonist that is being developed as a potential treatment for hypertension and diabetic nephropathy.

Search the web for more resources on

Web health.mongabay.com

Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com lead to other sites. health.mongabay.com does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com responsible for dead or misdirected links.