Myeloproliferative disease

This page contains recent news articles, when available, and an overview of Myeloproliferative disease but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Background information on Myeloproliferative disease

The myeloproliferative diseases are a group of diseases of the bone marrow where excess cells are produced. The delineation from leukemia is artificial, although the myeloproliferative diseases on the whole have a much better prognosis than the leukemias. The concept was first proposed in 1951 by the eminent hematologist William Dameshek.

The myeloproliferative diseases are:
  • Chronic myelogenous leukemia (CML)
  • Polycythemia vera (PCV)
  • Essential thrombocytosis (ET)
  • Myelofibrosis (increased connective tissue with decreased room for production of normal blood cells).
All MPDs arise from precursors of the "myeloid" lineage in the bone marrow. The lymphoid lineage may produce similar diseases, the lymphoproliferative disorders (acute lymphoblastic leukemia, lymphomas, chronic lymphocytic leukemia and multiple myeloma).
News Articles on Myeloproliferative disease



Cytopia Nominates JAK2 Clinical Candidate for Myeloproliferative ...  -  Mar 17, 2008
Earthtimes,This follows extensive laboratory experimentation and includes the recent demonstration of activity in an in-vivo model of myeloproliferative disease.

Upbeat outlook on life  -  Feb 29, 2008
Journal Times,When Blocks started the Myeloproliferative Disease Support Group, she thought it might just be her and another woman — the only other person she’d found in

TargeGen Announces Planned Initiation of Clinical Trial of JAK2 ...  -  Dec 6, 2007
ReutersTargeGen Announces Planned Initiation of Clinical Trial of JAK2 Inhibitor TG101348 in Myeloproliferative Disease Patients, and Presentations at ASH SAN

Rockefeller Cancer Center Work Coming  -  Dec 4, 2007
Houston Chronicle,...who died in July 2006 after unsuccessful treatment in Seattle for myeloproliferative disease, a blood disorder that can lead to leukemia.

Three Astex Drug Candidates to be Presented at the 2007 American ...  -  Nov 28, 2007
PR Newswire (press release),Is Active in JAK2 V617F Myeloproliferative Disease Models. Session Name: Myeloproliferative Syndromes: Therapy Session Date: Monday, December 10,

Portal vein thrombosis is common in extraportal vein obstruction  -  Oct 12, 2007
HULIQ,The role of JAK2mutation in the early diagnosis of overt or silent myeloproliferative disease cannot be undermined but requires standardization.

Arkansas News Bureau  -  Sep 29, 2007
Arkansas News,...bone marrow transplants at a Seattle cancer center in an attempt to treat his myeloproliferative disease, a blood disorder related to leukemia.

Ark. Cancer Center renamed for Win Rockefeller  -  Sep 28, 2007
Pine Bluff Commercial,Rockefeller died in July 2006 after unsuccessful treatment in Seattle for myeloproliferative disease, a blood disorder that can lead to leukemia. He was 57.

VAI scientists closer to finding leukemia gene  -  Aug 28, 2007
Rapid Growth,Researchers at Grand Rapids-based Van Andel Research Institute may have pinpointed the gene that causes myeloproliferative disease (MPD) and myelodysplastic

American Cancer Society Pays Tribute To Late Lt. Gov. Rockefeller.  -  Aug 25, 2007
Today's THV,His death marked the end of a courageous battle against myeloproliferative disease, a rare form of leukemia. The American Center Society honored Mr.

September support groups  -  Aug 24, 2007
Journal Times,For people with a myeloproliferative disease including essential thrombocytosis, polycythemia vera and myelofibrosis, 1:30 pm, Sept.

Researchers link gene, leukemia  -  Aug 24, 2007
The Grand Rapids Press - MLive.com,...likely will spend several more years analyzing what it means for people suffering from myeloproliferative disease, or MPD, and myelodysplastic syndrome,

Pre-cancerous Blood Diseases Can Be Products Of Their Environment  -  Jun 14, 2007
Science Daily (press release)Now, her team has found that the animals also develop myeloproliferative disease, in which the stem cells in bone marrow produce too many blood cell

Falls Church Resident Susan Diane Kaye Passes Away  -  May 9, 2007
Falls Church News Press,...be made to The Stem Cell Research Foundation, www.stemcellresearchfoundation.org or the Myeloproliferative Disease Research Fund at www.mpdhopkins.org.

On the Trail of a Point Mutation  -  Dec 9, 2006
Scientist,Prchal and Robert Kralovics had observed that many patients with myeloproliferative disease had a loss of heterozygosity (LOH) in the tip of the short arm of ...

Heart-health meds may cause leukemia  -  Nov 2, 2006
United Press InternationalMost of the enzyme-deficient mice developed myeloproliferative disease, a precursor to CML, and 15 percent had full-blown leukemias. ...



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