Fibroblastic

This page contains recent news articles, when available, and an overview of Fibroblastic but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Background information on Fibroblastic

A fibroblast is a cell that makes the structural fibers and ground substance of connective tissue. It has a branched cytoplasm surrounding an elliptical, speckled nucleus having 1 or 2 nucleoli. Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum. Inactive fibroblasts, which are also called fibrocytes, are smaller and spindle shaped. They have a reduced rough endoplasmic reticulum.

Fibroblasts make collagens, glycosaminoglycans, reticular and elastic fibers, and glycoproteins found in the extracellular matrix. In growing individuals fibroblasts are dividing and synthesizing ground substance. Tissue damage stimulates fibrocytes and induces the mitosis of fibroblasts.

Fibroblasts can give rise to other cells, such as bone cells, fat cells, and smooth muscle cells. Note that all of these cells are of mesodermal origin.

See also: fibrocartilage callus

News Articles on Fibroblastic

Veteran Leon High teacher gets support in battle against cancer  -  Mar 5, 2008
Tallahassee Democrat,She has fibroblastic osteosarcoma, an aggressive bone cancer that was diagnosed in September. The group hadn't seen each other since the school's pep rally

ccl21 expression pattern of human secondary lymphoid organ stroma ...  -  Nov 2, 2007
Am J Pathology (subscription)...localized in extra-hev position and organized in a fibroblastic reticular network similarly characterizes human slos and organized elts. altogether,

Study determines how viruses evade T-cells  -  Sep 19, 2007
United Press International...a chronic strain of lymphocytic choriomeningitis virus targeted a type of stromal cell in the lymphoid organs called fibroblastic reticular cells.

Chronic Infection Persists By Targeting Stromal Cell Network In ...  -  Sep 18, 2007
Science Daily (press release)...strain of lymphocytic choriomeningitis virus (LCMV) targeted a type of stromal cells in the lymphoid organs called fibroblastic reticular cells (FRC).

TGF--induced EMT: mechanisms and implications for fibrotic lung ...  -  Aug 29, 2007
AJP-Lung Physiology (subscription)AEC in IPF are morphologically abnormal, with hyperplastic pneumocytes and reactive elongated cells overlying fibroblastic foci, the presumed sites of

Inflammatory Myofibroblastic Tumor of the Paratestis  -  Aug 22, 2007
Journal of Ultrasound in Medicine (subscription)...[Medline] Nonaka D, Birbe R, Rosai J. So-called inflammatory myofibroblastic tumour: a proliferative lesion of fibroblastic reticulum cells?

Full Text  -  Aug 2, 2007
Science Magazine (subscription)CCL21 expression by fibroblastic reticular cells (FRCs) of the T cell zones in the spleen and lymph nodes (LN) facilitates effective interaction between

Relay Rally Inspires Teams for June 2-3 Event  -  May 15, 2007
Signal,He is also a cancer survivor - of very rare fibroblastic sarcoma. Dave Koppenhaver described his son's symptoms as strange speech, "snoring like an 80

Expression of RANKL in Osteolytic Membranes: Association with ...  -  Apr 2, 2007
Journal of Bone and Joint Surgery (subscription)Samuel C. Ramage 1 , Nicole H. Urban, PhD 1 , William A. Jiranek, MD 1 , Aparna Maiti, PhD 1 and Matthew J. Beckman, PhD 1

Sonographic Features With Histopathologic Correlation  -  Nov 22, 2006
Journal of Ultrasound in Medicine (subscription)...of elastic fibers; (2) deposits of calcium and hemosiderin, both in vessels and in intervening connective tissue stroma; (3) a fibroblastic reaction and ...

Benefit dinner and auction set for three area residents  -  Oct 28, 2006
Twin Falls Times-News,Jo Osterhout who has amyloidasis cancer, and Brett Blacker, 15-year-old son of Rodney and Marla Blacker, who has been diagnosed with fibroblastic osteosarcoma. ...

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