Ataxia-Telangiectasia

This page contains recent news articles, when available, and an overview of Ataxia-Telangiectasia but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Background information on Ataxia-Telangiectasia

Ataxia-telangiectasia (AT) is a primary immunodeficiency disorder that occurs in an estimated incidence of 1 in 40,000 to 1 in 300,000 births (Lederman, 2000). AT is characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, progressive cerebellar dysfunction, and recurrent sinopulmonary infections secondary to progressive immunological and neurological dysfunction (Boder, 1958). AT patients are significantly predisposed to cancer, particularly lymphomas and leukemias. Other manifestations of the disease include sensitivity to ionizing radiation (Taylor et al., 1975), premature aging, and hypogonadism (Regueiro et al., 2000). AT has been a major interest of scientists since the 1960’s because it may yield an insight into numerous other major health problems, such as cancer, neurological disease, immunodeficiency, and aging (Lederman, 2000).
News Articles on Ataxia-Telangiectasia



Olympic Triathlete Hunter Kemper Named Honorary Coach for Charity ...  -  Mar 3, 2008
PR Urgent...and Mary Veldink and learned that two of their children, Kate (age nine) and Olivia (age six) had both been diagnosed with ataxia-telangiectasia, or AT.

Villager hosting benefit line dance to raise funds for research of ...  -  Mar 4, 2008
Villages Daily Sun,...when her niece Melissa — or “Missy� as her family calls her — died four years ago from leukemia brought on by the condition Ataxia-Telangiectasia.

Full Text  -  Mar 6, 2008
Science Magazine (subscription)In the precancerous lesions, before p53 mutations were acquired, 53BP1 localized at foci and histone H2AX, ataxia telangiectasia (ATM), Chk2,

Miss Oshkosh Crowned  -  Mar 2, 2008
Advance Titan,...performed a tap dance routine to “Sing, Sing, Sing�, and answered a question about her platform on Ataxia-Telangiectasia (AT) awareness and research,

Anti-malarial prevents cancer in mice  -  27 Dec 2007
HULIQ,...drug chloroquine effectively prevents cancer in mouse models of two distinct human cancer syndromes, Burkitt lymphoma and ataxia telangiectasia.

Commentary: The Christmas Spirit encompasses all of us, able ...  -  Dec 21, 2007
The Reporter,Dan was born with the rare genetic disease called Ataxia-telangiectasia. You can reach her at chattykathyko@hotmail.com.

Joshua Bryan Stamm  -  Dec 20, 2007
Goshen Chronicle15, 2007 at Orange Regional Medical Center in Goshen after a courageous fight with health conditions associated with his disability — Ataxia Telangiectasia.

SECOND TRAGEDY HITS MUM AS FATAL ILLNESS CLAIMS ANOTHER SON  -  Dec 5, 2007
Express & Echo,Aaron suffered from ataxia-telangiectasia - a rare and incurable degenerative genetic disorder also known as AT, which affects just 150 people in Britain.

p53 decline in old age: a cause of late-life cancer?  -  Dec 13, 2007
Methuselah Foundation,The function of the Ataxia-telangiectasia mutated (ATM) kinase declined significantly with age, which may then be responsible for the decline of the p53

clinical and laboratory features of ataxia telangiectasia  -  Nov 1, 2007
AAP Grand Rounds (subscription),...source: moin m, aghamohammadi a, kouhi a, et al. ataxia-telangiectasia in iran: clinical and laboratory features of 104 patients. pediatr neurol.

ataxia-telangiectasia (at) is a progressive, degenerative disease ...  -  Oct 27, 2007
Carlisle Sentinel,...diagnosed at age 7, klein is a survivor of what scientists call ataxia-telangiectasia — a progressive, degenerative disease that attacks a variety of body

the atr-mediated s phase checkpoint prevents rereplication in ...  -  Nov 19, 2007
Journal of Cell Biology (subscription)...ensuring that each origin fires once and only once per cell cycle. we demonstrate that the ataxia telangiectasia and rad3 related (atr)–mediated s phase

running notebook 63 marathons in 63 days worth the effort  -  Nov 14, 2007
Houston Chronicle,...and i had spoken with him on the phone about his quest to raise funds for — and awareness of — ataxia-telangiectasia, or at, a rare fatal genetic

rare disease inspires man's 63-marathon streak  -  Nov 5, 2007
NPR...borland ran most of his races pushing a jogging stroller that was often occupied by a child or teenager with ataxia-telangiectasia, a rare genetic disease.

couple captures man's 63 days of running marathons  -  Nov 17, 2007
Oshkosh Northwestern,...the couple was intrigued. running to raise awareness for children who suffer from debilitating, fatal ataxia-telangiectasia, tim borland's third-party

marathoner races to battle disease  -  Nov 3, 2007
Connecticut Post,...an organization that raises money to find a cure for ataxia telangiectasia, also known as at, which is aa lethal genetic disease that attacks children,

uw-oshkosh students hold telethon  -  Nov 10, 2007
CBS 5 - Green Bay,...oshkosh (wfrv) - radio, tv and film students from uw-oshkosh are broadcasting the 6th ataxia-telangiectasia telethon live tonight from 4pm until midnight.

researchers look to malaria medication to prevent or delay ...  -  Nov 7, 2007
News from Washington University in St. Louis,...that makes an enzyme called atm (ataxia telangiectasia mutated). children without the gene develop a serious disorder called ataxia telangiectasia (at).

marathon man runs in stratford  -  Nov 2, 2007
WTNH,...he's motivated by children like rob smarz, 15, from stratford. rob is afflicted with a rare genetic disease called ataxia-telangiectasia or at.

running with a mission to save children with rare disease  -  Oct 29, 2007
WAVY-TV,...tim borland in the williamsburg leg of a series of marathons to raise money for a condition lewin was diagnosed with at age 4: ataxia-telangiectasia

one step at a time: 63 marathons in 63 days  -  Nov 1, 2007
ABC News...of his running sneakers and each step on the pavement he'll be raising awareness and money aimed at finding a cure for ataxia-telangiectasia, or at,

63 marathons for $2 million  -  Nov 5, 2007
Daily Press,...ago. borland ran 63 marathons in 63 days to raise money and awareness for ataxia-telangiectasia (at), a rare genetic disease that strikes children,

editorial: plenty of things we can all be thankful for  -  Nov 22, 2007
Oshkosh Northwestern,...tv and film students pulling off another successful telethon to raise money to combat the rare genetic childrens' disease, ataxia-telangiectasia? this

american donors put faith (and dollars) in tau cancer research  -  Nov 13, 2007
EurekAlert (press release),...made his first breakthrough in cancer research in 1995 when he discovered the gene for the rare genetic disease ataxia-telangiectasia (at). he remarks,

telethon tops $7k in last minutes  -  Nov 11, 2007
Advance Titan,...sixth annual at telethon saturday. the telethon, which raises awareness of and money to find a cure for a deadly disease called ataxia-telangiectasia,

art gala in 'black and white'  -  Nov 7, 2007
Chicago Daily Southtown,...also known as ataxia telangiectasia, a genetic disease that attacks during early childhood. nancy mitchell, co-chairwoman of the gala, said committee

the causes that inspired central coast residents to finish the new ...  -  Nov 5, 2007
KSBY,...awareness and money to find a cure for ataxia-telangiectasia or at, a rare and terminal genetic disease in children that causes loss of muscle control.

marathon runner completes 62nd run  -  Nov 3, 2007
Providence Journal,...ataxia-telangiectasia (at) — was far too great to alter his nationwide plan, 63 marathons in 63 days. he began at disneyland, in california, on sept.

a real marathon man: montclair stop no. 57 for californian running ...  -  Nov 1, 2007
Montclair Times,...of los gatos, calif., is running a marathon each day for 63 days in the at cure tour to raise money and awareness for ataxia-telangiectasia or at,

students have sense of purpose  -  Oct 29, 2007
Checkbiotech.org (press release),...proceeds will benefit torey ribaudo, a seventh-grader who suffers from a rare disorder called ataxia-telangiectasia and was recently diagnosed with



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